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Biomni uses conversation context, personal instructions, and project settings at different scopes. Choose the narrowest scope that fits the instruction.

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Conversation context

Within a task, Biomni can use earlier messages, attached files, and generated results. Keep follow-up refinements in the same task:
Start a new task when the goal or evidence boundary changes substantially.

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Personal instructions

Open Settings → Personalization and add entries under Custom Instructions. Add durable preferences such as:
  • preferred programming language;
  • desired figure or report format;
  • terminology and units to use; or
  • response conventions you want across tasks.
Personal instructions are stored for your user in the active workspace and are included when Biomni starts work. You can edit or remove them at any time.
Write preferences as direct instructions: “Use R for statistical analysis” is clearer than “I sometimes prefer R.”

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Project settings

Use Settings → Projects for context or instructions that apply only to one project. Project settings include:
  • project context;
  • ordered custom instructions; and
  • auto attached Skills for the first message of new tasks.
Project instructions are more specific than personal instructions. Changes are captured by new tasks and do not rewrite existing conversations.

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What not to store

Do not put passwords, API keys, access tokens, private keys, or other credentials in personal or project instructions. Use approved connection and secret-management flows instead. For project-level configuration, see Projects & Drive.